Clinical Research

The BI-LO Charities Children’s Cancer Center is committed to its mission, and this is evident in its membership in the Children's Oncology Group. Through its full-time and active membership in this international childhood cancer research group, the Center has been able to provide all of its oncology patients’ access to the most current research drug trials and protocols.

Initially the Center was part of the Pediatric Oncology Group (POG) and currently is a member of the Children’s Oncology Group (COG), which was formed by the merging of the Pediatric Oncology Group (POG), the Children’s Cancer Group (CCG), the International Rhabdomyosarcoma Group, and the National Wilms’ Tumor Study Group in 2000.

About 90% of all children with cancer in the U.S. are treated according to Children’s Oncology Group protocols. The BI-LO Charities Children’s Cancer Center currently has 64 active protocols, and greater than 95% of our cancer patients are treated according to these protocols. Treatment by these protocols, plus careful monitoring of side effects, results in a cure rate of approximately 80% of all children with cancer. This cure rate contrasts with a cure rate of approximately 45 to 50% in adult patients.

Maintaining a membership in COG means much “behind the scenes” work. Our new protocols are presented to the Greenville Health System Internal Review Board (IRB) for approval, and they must be updated and re-approved at least yearly. Our Center submits data from our patients to the COG National Data Office, and we receive updates on protocols continually. Specially trained nurses and clinical research assistants (CRAs) work with the physicians to keep our research data accurate and up-to-date. Physicians, nurses, and support medical staff from the BI-LO Charities Children’s Cancer Center attend COG meetings every six months to receive education, information, and changes that are happening with COG protocols and research.

In addition to education and research, COG also requires the BI-LO Charities Children’s Cancer Center to go through inspections and audits regarding the use of the protocols and patient care. These audits are done every three years by COG trained physicians. Since the its inception in 1986, The BI-LO Charities Children’s Cancer Center has passed all 7 audits without ever needing a re-audit, indicating that our Center meets or exceeds the standards set by the National Cancer Institute and the Children’s Oncology Group. We work continuously to follow the strict guidelines set by the COG protocols because it not only ensures that we pass our audits, but it translates into better care and higher survival rates for our patients.

Dr. Cary Stroud